Vardenafil works by increasing blood flow to the penis during sexual stimulation, thus helping men achieve and maintain an erection. Zhewitra 60 is typically taken orally, with or without food, about 30 minutes to 1 hour before sexual activity. The effects of the medication can last for up to 4-5 hours. Additionally, like all medications, Zhewitra 60 mg may cause side effects in some individuals, such as headache, flushing, dizziness, and upset stomach. If you experience any severe or persistent side effects, it's crucial to seek medical attention promptly.